cyclophosphamide

n an ALKYLATING AGENTS used to treat a variety of cancers, often in combination with other CYTOTOXIC DRUG . It also has IMMUNOSUPPRESSION properties and is used in treating conditions, notably rheumatoid arthritis, requiring a reduced immune response. Cyclophosphamide is administered by mouth or by injection; common side-effects are nausea, vomiting, and - particularly at high doses - hair loss. Trade name: Endoxana.