phenylephrine
a drug that constricts blood vessels (see SYMPATHOMIMETIC ). It is given by injection to increase blood pressure, in a nasal spray to relieve nasal congestion, and in eye drops to dilate the pupils. Irritation may occur when applied.
Phenylephrine is used to relieve nasal discomfort caused by colds, allergies, and hay fever. It is also used to relieve sinus congestion and pressure. Phenylephrine will relieve symptoms but will not treat the cause of the symptoms or speed recovery. Phenylephrine is in a class of medications called nasal decongestants. It works by reducing swelling of the blood vessels in the nasal passages.
Full drug information on MedlinePlus →This is general information, not medical advice. Pregnancy and breastfeeding decisions should always be made with your healthcare provider.
Can taking phenylephrine affect fertility or make it harder to get pregnant?
It is not known whether phenylephrine can make it harder to get pregnant. If you have concerns about fertility, it's best to discuss them with your healthcare provider.
Does taking phenylephrine increase the risk of miscarriage?
Miscarriage can occur in any pregnancy for many reasons. The fact sheet notes that studies have not been done to determine whether phenylephrine increases the chance of miscarriage. Any questions about your individual situation should be discussed with your healthcare provider.
Does taking phenylephrine increase the risk of birth defects?
The fact sheet states that studies involving more than 1,500 people who took phenylephrine in the first trimester did not show an increased chance of birth defects, though one study of 1,249 people reported a slightly higher chance of minor differences of the eyes or ears (not considered birth defects). Studies on other medications that work similarly (constricting blood vessels) have raised questions about a small possible increase in birth defects. Your healthcare provider can help you weigh this information for your situation.
Can taking phenylephrine during pregnancy cause other pregnancy-related complications?
It is not known whether phenylephrine increases the chance of issues like preterm delivery or low birth weight. Because phenylephrine narrows blood vessels, there are theoretical (unproven) concerns about reduced blood flow through the placenta, and it could also raise blood pressure. People with high blood pressure are encouraged to talk with their healthcare provider about which medications are best for them.
Can taking phenylephrine during pregnancy affect the child's brain development, learning, or behavior?
The fact sheet indicates that studies have not been done to see whether phenylephrine affects future behavior or learning in the child. Questions about long-term child development are best discussed with your healthcare provider.
Is it safe to breastfeed while taking phenylephrine?
The fact sheet notes that studies have not been done to see whether phenylephrine passes into breast milk, and animal studies suggest it might reduce milk supply. Because there is little information on oral phenylephrine while breastfeeding, nasal sprays or other medications might be preferred. Discuss your breastfeeding questions with your healthcare provider.
Source: National Library of Medicine
phenylephrine