hydrocortisone

a STEROID glucocorticoid HORMONE produced and released by the CORTEX of the ADRENAL GLANDS (a CORTICOSTEROID ). It is closely related to CORTISONE , being released in response to stress and playing a significant part in carbohydrate METABOLISM . Medically it has a number of uses, especially in the treatment of ADDISON'S DISEASE , inflammatory, allergic and rheumatic conditions, e.g. eczema and rheumatoid arthritis. Hydrocortisone is contained in ointments in creams or given by mouth or injection, depending on the condition under treatment. Prolonged use may cause SIDE EFFECTS , including PEPTIC ULCERS , stunting of growth in children, CUSHING'S SYNDROME and damage to bone and muscle tissue.