fluorouracil

n a drug that prevents cell growth ( see antimetabolite ) and is used in the treatment of cancers of the digestive system and breast (see also folinic acid ). It is usually administered by injection. Side-effects, which may be severe, include digestive and skin disorders, mouth ulcers, hair loss, nail changes, and blood disorders. Fluorouracil is also applied as a cream ( Efudix) to treat certain skin conditions, including skin cancer.