alprostadil

a PROSTAGLANDIN drug (PGE1) administered by infusion to improve lung blood flow in newborn babies with congenital heart defects who are awaiting surgery; it acts by preventing the closure of the blood vessel connecting the aorta to the pulmonary artery ( see DUCTUS ARTERIOSUS ). Possible side-effects include diminished respiratory efforts. Alprostadil is also administered by injection into the corpora cavernosa of the penis or by application into the urethra to treat erectile IMPOTENCE in men; side-effects may include dizziness and headache. Trade names: Caverject, MUSE, Prostin VR.